Journal of Wound Care, Vol. 21, Iss. 12, 11 Dec 2012, pp 612 - 614
Objective: To determine the effect of topically applied amelogenin extracellular matrix protein (AEMP) in patients with non-healing venous leg ulcers combined with atrophie blanche.
Method: This retrospective case series of patients with non-healing venous leg ulcers with atrophie blanche of the distal proportion of their lower legs, where non-healing was defined as no progress toward healing for 3 months previously, under standard therapy. Patient records were reviewed for associated diseases, wound diagnoses, distal blood pressure, previous treatments and changes in wound area. Patients were treated with AEMP once a week, for a period of 12 weeks, or until full healing.