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S. Läuchli, J. Hafner, C. Wehrmann, L.E. Frenc
Journal of Wound Care, Vol. 21, Iss. 5, 10 May 2012, pp 228 - 233

Objective: To evaluate the efficacy of a plant-derived wound dressing, a mixture of hypericum oil (Hypericum perforatum) and neem oil (Azadirachta indica), in scalp wounds with exposed bone.
Method: A retrospective review was conducted of all patients presenting with scalp wounds with
exposed bone following the excision of skin tumours and treated with a plant-derived wound dressings (1 Primary Wound Dressing; Phytoceuticals AG), from January to July 2011. Time to healing, wound size, area of exposed bone, ease of handling, pain and complications were evaluated.
Results: Nine consecutive patients were analysed retrospectively. The patients' mean age was
81.2 ± 8.5 years (63-90 years), with a mean wound size of 13.2 ± 6.8cm2 (0.4-22.6cm2) and 6.8 ± 6.5cm2 (0.3-20.7cm2) of exposed bone. The time to complete healing by secondary intention was 4-20 weeks. A rapid induction of granulation tissue was observed, which covered the entire exposed bone surface in six out of nine cases (67%) after 4 weeks, and showed a reduction in the mean area of exposed bone of 95%. Dressing change was easy and without pain and there were no complications.
Conclusion: This retrospective, non-controlled analysis suggests that ONE is a very simple to use, safe and potentially effective therapy for the treatment of scalp wounds with exposed bone.
Declaration of interest: There were no external sources of funding for this study. The authors have no conflict of interest to declare.

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